Physiological and Biotechnological Aspects of Extremophiles

Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.

The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.

Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms.

Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research

Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles

Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications

Preface & Intro & Acknowledgements

Physiological aspects

1. Overview of extremophiles

2. Physiology of Extremophiles

3. Mechanism of resistance focusing on copper, mercury and arsenic in extremophilic organisms, how acidophiles and thermophiles cope with these metals.

4. Halotolerant microbes and their applications in sustainable agriculture

5. Halophilic microorganisms: interesting group of extremophiles with important applications in biotechnology and environment

6. Overview of extremophiles and their food and medical applications

7. Applications of extremophiles in Astrobiology

8. High-pressureAdaptation ofExtremophiles and Biotechnological Applications

9. Fructanogenic Halophiles: A new Perspective on Extremophiles

10. Applications of sulfur-oxidizing bacteria

11. Physiological and genomic perspective of extremophiles in high salt concentrations

Biotechnological aspects

12. Genome editing in extremophiles using CRISPR/Cas9 technology

13. Lipases/esterases from extremophiles: main features and potential biotechnological applications

14. Thermostable ThermoanaerobacterAlcohol Dehydrogenases And Their Use In Organic Synthesis

15. Biotechnological platforms of the moderate thermophiles, Geobacillus species: notable properties and genetic tools

16. Thermophiles and Thermophilic Hydrolases

17. Effects of single nucleotide mutations in the genomes of multi-drug resistant 19biofilm producing Pseudomonas aeruginosa

18. Understanding the structural basis of adaptation in enzymes from psychrophiles

19. Molecular and functional characterization of major compatible solute in Deep Sea halophilic actinobacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India

20. Antarctic microorganisms as a source of biotechnological products

21. The Secretomes of Extremophiles

22. Carbonic anhydrase from extremophiles and their potential use in biotechnological applications

23. Understanding the Protein Sequence and Structural Adaptation in Extremophilic Organisms through Machine Learning Techniques

24. Exploration of extremophiles genomes through metagenomics for hidden Biotechnological and future potential

25. The Ecophysiology, Genetics, Adaptive Significance, and Biotechnology of Nickel Hyperaccumulation in Plants

Anthony Logan Ferrero, Peter R. Walsh and Nishanta Rajakaruna