Epigenetics of the Immune System

Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications.

Provides an overview of most important immune mechanisms, the current status of epigenetics, and how both of them are brought together Presents key principles of immune mechanisms in epigenetics, presenting current findings and key principlesFeatures in-depth chapter contributions from a wide range of international researchers and specialists in immunology, translational medicine and epigeneticsMerges two very large areas, covering the unique interrelatedness of epigenetics and immunology

Preface

1. An introduction to immunology and epigenetics Jaydeep Bhat, Dieter Kabelitz

2. Plant epigenetics and the “intelligent” priming system to combat biotic stress Hemlata Kotkar, Ashok Giri

3. Understanding immune system development: An epigenetic perspective Ayush Madhok, Anjali deSouza, Sanjeev Galande

4. Epigenetic mechanisms in the regulation of lymphocyte differentiation Nina Schmolka, Bruno Silva-Santos, Anita Q. Gomes

5. Epigenetics mechanisms driving immune memory cell differentiation and function Stephen J. Turner, Jasmine Li, Brendan E. Russ

6. Microbiota in the context of epigenetics of the immune system Katarzyna Placek

7. Sequencing technologies for epigenetics: From basics to applications Rosario Michael Piro

8. Advances in single-cell epigenomics of the immune system Jonas Schulte-Schrepping, Humberto J. Ferreira, Adem Saglam, Emily Hinkley, Joachim L. Schultze

9. Machine learning and deep learning for the advancement of epigenomics Magdalena A. Machnicka, Bartek Wilczynski

10. Systems immunology meets epigenetics Wenhui Li, Ziyi Chen, Aiping Wu, F. Xiao-Feng Qin, Lianjun Zhang

11. Epigenetic deregulation of immune cells in autoimmune and autoinflammatory diseases Javier Rodríguez-Ubreva, Tianlu Li, Esteban Ballestar

12. Epigenetics of allergies: From birth to childhood Avery DeVries, Donata Vercelli

13. Epigenetic regulation of normal hematopoiesis and its dysregulation in hematopoietic malignancies Mark Hartmann, Mariam Hakobyan, Jens Langstein, Maximilian Schonung, Sina Stäble, Aurore Touzart, Justyna A. Wierzbinska, Daniel B. Lipka

14. Impact of epigenetic modifiers on the immune system Sajad Ahmad Bhat, Shalini Kashipathi Sureshbabu, Chinna Susan Philip, Shubhada Chiplunkar

Index