Molecular Evolutionary Models in Drug Discovery

Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.

Examines the integration and application of evolutionary models in the pharmaceutical industry to create new drug development platformsInvestigates the biotechnological prospecting of secondary metabolites and their potential use in the discovery of new drugsEvaluates the ecosystem of living beings and how its molecular adaptation might improve the success of therapies

1. Introduction 2. Molecular Autopoiesis 3. Natural products and molecular networks 4. Symbiogenesis autopoietic 5. Metabolomic autopoiesis 6. Clinical outcome and autopoiesis 7. Toxical autopoiesis 8. Future Research and Applications