Dietary Sugar, Salt and Fat in Human Health

Divided into four main sections, Dietary Sugar, Salt and Fat in Human Health explores the biochemical, pharmacological and medicinal aspects related to the overindulgence of dietary salt, sugar, and fat, along with possible remedies.

Beginning with a general overview, the text outlines aspects associated with advancing age and human physiology, such as different aspects of insulin resistance, the advancing age phenomenon, central fat accumulation and metabolic perturbations and the role of the modern Western diet and the influence of dietary sugar, salt, and fat, with particular focus on their relation to multiple biochemical pathophysiological pathways. The second section of the book focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic, with an emphasis on carbohydrate metabolism and its biochemistry, GI absorption, the glycemic index and the influence of fructose. The historical background of dietary sugars is discussed alongside Atkin’s hypothesis, and an overview of the correlation between dietary fibre and the glycemic index, including a chapter on sugar addiction. Section three contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects, including salt-sensitive hypertension, contribution of two steroid receptor pathways, vascular NO, intrarenal RAAS system and angiotensin. The fourth section highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases, and further explores NAFLD and gender specific problems. Chapters in this section also investigate the benefits of the Mediterranean diet as well as myths related to cholesterol.

Collected and carefully organized for researchers in nutrition, physiology, epidemiology, or sensory science, this book will also benefit general practitioners, surgeons, nurses, health professionals and practitioners, and students studying the role of diet in cardiometabolic disorders and disease.

Demonstrates how a healthy lifestyle impacts lifespanProvides a general overview and outlines aspects associated with advancing age and human physiologyFocuses on the roles of dietary sugars and their correlation with the chronic disease epidemicContains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspectsHighlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases

General Background 1. Epidemiological Perspectives of Dietary Sugars, Salts and Fats 2. Advancing Age, Influence of Dietary Sugars, Salts and Fats on Metabolic Disorders and Chronic Diseases 3. Dietary Fat, Salt and Sugar: A clinical perspective of the social catastrophe 4. Influences of Food Ingredients on Enterohepatic Circulation of Bile Acids 5. Anemia: Influence of Dietary Fat, Sugar and Salt on Hemoglobin and Blood Health

Food Behavior, Food Addiction and Metabolic Syndrome 6. Drivers of Food Behavior 7. Focusing the Fight Against Processed Food Addiction (PFA) 8. Dietary Influences on Pediatric Obesity and Metabolic Syndrome 9. An Overview of Addiction to Sugar

Dietary Sugar And Health 10. Influence of Dietary Sugars on Blood Pressure Regulation: Historical, Epidemiological, Laboratory, and Clinical Considerations 11. Glycation induced protein aggregation and cellular toxicity: An insight into the disease realm of high dietary sugar intake 12. Probing Various Pro and Con Health Aspects of the Glucose-Insulin System in Non-Diabetics: Focusing on Insulin Resistance and Dietary Implications 13. Evaluating Proposed Surrogates to Estimate Insulin Resistance in Non-Diabetics: Emphasizing Ratio Triglycerides/HDL-Cholesterol vs. Fasting Blood Glucose 14. Associations of high blood sugar with oxidative stress and inflammation in patients with type 2 diabetes 15. Assessing The Triglyceride/Hdl-Cholesterol Ratio As A Surrogate For Insulin Resistance And Its Link To The Metabolic Syndrome In Hispanics And African-Americans 16. The benefit of Indian Jaggery over sugar on human health 17. Linking Fasting Blood Glucose (FBG) Quartiles of Non-Diabetic Volunteers Ages 21-84 Years to Metabolic Syndrome Components

Overindulgence Of Dietary Salt 18. Salt-Induced Inappropriate Augmentation of Intrarenal RAAS System: Chronic Renal Diseases 19. Table Salt (Sodium Chloride): Vital Aspects Of Metabolism And Blood Pressure Regulation In Health And Disease 20. Nutraceuticals and functional foods in the prevention of Hypertension induced by excessive intake of dietary salt

Dietary Fat & Cholesterol 21. Physiological Role of Cholesterol in Human Body 22. Interplay between dietary sugars and fats and insulin resistance 23. Erythrocyte membranes in metabolic and neurological diseases – supplementation with fatty acids and membranes remodeling

Dietary Fiber, Ketogenic Diets & Benefits 24. Dietary Fiber: A Functional Food Ingredient with Physiological Benefits 25. Ketogenic and low carbohydrate diets in health and disease 26. Dietary Fat, Salt and Sugar - A Teenager’s View

Commentary from the Editors' Desk