Introduction to Addiction: Addiction, Animal Models, and Theories

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse.

Provides neurobiological theories on how addiction worksExplains addiction cycle stages of binge, withdrawal and anticipationReviews the role of dopamine and the frontal cortex in addictionDiscusses the neurocircuitry of reward and stressIncludes animal models and neuroadaptational views on addiction

WHAT IS ADDICTION? 1. Definitions of Addiction 2. Neuroadaptational Views of Addiction 3. Neuroadaptational Summary 4. Summary

ANIMAL MODELS 5. Definitions and Validation of Animal Models 6. Animal Models of the Binge-Intoxication Stage of the Addiction Cycle 7. Animal Models of the Withdrawal/Negative Affect Stage of the Addiction Cycle 8. Animal Models of the Preoccupation/Anticipation Stage of the Addiction Cycle 9. Animal Models of Vulnerability to Addiction 10. Summary

NEUROBIOLOGICAL THEORIES 11. Neurocircuitry Hypotheses of Addiction—Dopamine 12. Neurocircuitry Theories of Addiction—Frontal Cortex 13. Neurocircuitry Theories of Addiction—Relapse 14. Neurocircuitry Theories of Addiction—Reward and Stress 15. Cellular Hypotheses of Addiction 16. Molecular Hypotheses of Addiction 17. Synthesis: Common Elements of Most Neurobiological Models of Addiction