New Therapeutic Strategies for Brain Edema and Cell Injury

New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 145, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this volume presenting interesting chapters on the Blood-brain barrier breakdown and brain edema formation in Alzheimer’s disease, Blast brain Injury induced edema formation and therapeutic measures, Brain edema in Parkinson’s disease. Novel therapeutic strategies, Brain edema and blood-brain barrier breakdown in sleep deprivation. Therapeutic potential of cerebrolysin, Differential cell injury induced by NMDA antagonist MK 801 in early age, Anesthetics influence Brain edema in concussive head injury, and more.

Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the International Review of Neurobiology seriesUpdated release includes the latest information on New Therapeutic strategies for Brain Edema and Cell Injury

1. 5-hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology Aruna Sharma, Rudy J. Castellani, Mark A. Smith, Dafin F. Muresanu, Prasanta Kumar Dey and Hari S. Sharma 2. Anaesthetics influence concussive head injury induced blood-brain barrier breakdown, brain edema formation, cerebral blood flow, serotonin levels, brain pathology, and functional outcome Hari S. Sharma, Dafin F. Muresanu, Ala Nozari, Rudy J. Castellani, Prasanta K. Dey, Lars Wiklund and Aruna Sharma 3. Exacerbation of blood-brain barrier breakdown, edema formation, nitric oxide synthase upregulation, and brain pathology after heat stroke in diabetic and hypertensive rats: Potential neuroprotection with cerebrolysin treatment Dafin F. Muresanu, Aruna Sharma, Ranjana Patnaik, Preeti K. Menon, Herbert Mössler and Hari Shanker Sharma 4. Neuroprotective effects of a potent bradykinin B2 receptor antagonist HOE-140 on microvascular permeability, blood flow disturbances, edema formation, cell injury, and nitric oxide synthase upregulation following trauma to the spinal cord Hari Shanker Sharma, Lianyuan Feng, Dafin Fior Muresanu, Rudy J. Castellani and Aruna Sharma 5. Potentiation of spinal cord conduction and neuroprotection following nanodelivery of DL-3-n-butylphthalide in titanium implanted nanomaterial in a focal spinal cord injury induced functional outcome, blood-spinal cord barrier breakdown and edema formation Seaab Sahib, Feng Niu, Aruna Sharma, Lianyuan Feng, Z. Ryan Tian, Dafin F. Muresanu, Ala Nozari and Hari Shanker Sharma 6. Leakage of the blood-brain barrier followed by vasogenic edema as the ultimate cause of death induced by acute methamphetamine overdose Eugene A. Kiyatkin and Hari S. Sharma 7. Neuroprotective effects of 5-HT3 receptor antagonist ondansetron on morphine withdrawal induced brain edema formation, blood-brain barrier dysfunction, neuronal injuries, glial activation, and heat shock protein upregulation in the brain Aruna Sharma, Ranjana Patnaik and Hari Shanker Sharma 8. Therapeutic potential of cannabinoids as neuroprotective agents for damaged cells conducing to movement disorders Mario Antonazzo, María Botta, Harkaitz Bengoetxea, José Ángel Ruiz-Ortega and Teresa Morera-Herreras 9. Dysfunction of serotonergic neurons in Parkinson’s disease and dyskinesia Vegas-Suarez Sergio, Paredes-Rodriguez Elena, Aristieta Asier, Lafuente Jose V., Miguelez Cristina, Ugedo Luisa 10. New therapeutic approaches to target alpha-synuclein in Parkinson’s disease: The role of immunotherapy Fernández-Valle T., Gabilondo I. and Gómez-Esteban J.C.