Biotin and Other Interferences in Immunoassays: A Concise Guide

Biotin and Other Interferences in Immunoassays: A Concise Guide is aimed at clinical laboratory scientists, medical technologists and pathologists who are often the first individuals contacted by a clinician when a laboratory test result does not correlate with clinical presentation. Research scientists working in diagnostics companies will also find this information essential. Sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratory are also discussed so readers can get all important information from one concise guide. This succinct, user-friendly reference provides the necessary information to address high levels of biotin in clinical laboratory results.

Discusses issues of biotin interferences and ways to avoid them for accurate clinical laboratory resultsProvides sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratoriesHighlights how to handle specimens in the lab and how to eliminate the effect of biotin in precious samples

1. Immunoassay design and mechanism of biotin interference 2. Biotin: Pharmacology, Pathophysiology and Assessment of Biotin Status 3. Biotin: From Supplement to Therapy 4. Effect of Biotin on Clinical Laboratory Test Results: How to Avoid such Interferences? 5. Issues of Interferences in Clinical Chemistry Tests including Heterophilic Antibody Interferences 6. Issues of Interferences in Therapeutic Drug Monitoring 7. Issues of Interference in Drugs of Abuse Testing and Toxicology