The Artificial Pancreas: Current Situation and Future Directions

The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient’s quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.

Focuses on Type 1 Diabetes Mellitus (T1DM) that is primarily found in children and typically treated by means of a syringe or insulin pumpFeatures research and results from top academic experimental groups, and from universities such as Harvard (USA), the University of Virginia (USA), the University of Padova (Italy), the University of Montpellier (France), and the Buenos Aires Institute of Technology (Argentina)Discusses clinical trials of AP from around the world, including the United States, the EU, Latin America, and Israel

1. Feedback control algorithms for automated glucose management in T1DM: the state of the art
2. Getting IoT-ready
3. Multivariable AP with adaptive control
4. The ARG algorithm: clinical trials in Argentina
5. Use of intraperitoneal insulin delivery for artificial pancreas
6. Physiological models for artificial pancreas development
7. Deployment of modular MPC for type 1 diabetes control: the Italian experience 2008–2016
8. Integrating the clinical and engineering aspects of closed-loop control: the Virginia experience
9. Strategies to mitigate hypoglycaemia in the artificial pancreas
10. Multiple-signal artificial pancreas systems
11. Artificial pancreas in pediatrics