Cell Volume Regulation

Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the Current Topics in Membranes seriesUpdated release includes the latest information on the Cell Volume Regulation and Fluid Secretion

Section 1. General Principles of Cell Volume Regulation 1. Water Homeostasis and Cell Volume Maintenance and Regulation Eric Delpire and Kenneth B. Gagnon 2. Search for Upstream Cell Volume Sensors: The Role of Plasma Membrane and Cytoplasmic Hydrogel Sergei N. Orlov, Aleksandra Shiyan, Francis Boudreault, Olga Ponomarchuk, and Ryszard Grygorczyk 3. Cytoskeletal Contribution to Cell Stiffness Due to Osmotic Swelling; Extending the Donnan Equilibrium Pei-Chuan Chao, Mettupalayam Sivaselvan, and Frederick Sachs 4. Membrane Stiffening in Osmotic Swelling: Analysis of Membrane Tension and Elastic Modulus Manuela A.A. Ayee and Irena Levitan 5. Molecular Identities and ATP Release Activities of Two Types of Volume-Regulatory Anion Channels, VSOR and Maxi-Cl Yasunobu Okada, Toshiaki Okada, Md. Rafiqul Islam, and Ravshan Z. Sabirov 6. Molecular Biology and Physiology of LRRC8 Volume-Regulated Anion Channel (VRAC) James Osei-Owusu, Junhua Yang, Maria del Carmen Vitery, and Zhaozhu Qiu

Section 2. Regulation of Intracellular Chloride and Water Homeostasis 7. Role of WNK Kinases in the Modulation of Cell Volume Paola de los Heros, Diana Pacheco-Alvarez, and Gerardo Gamba 8. Intracellular Macromolecules in Cell Volume Control and Methods of Their Quantification Michael A. Model M.A. and Jonathan C. Petruccelli

Section 3. Cell Volume Regulation in the Airways 9. Slippery When Wet: Airway Surface Liquid Homeostasis and Mucus Hydration Megan J. Webster and Robert Tarran 10. Physiology of the Gut: Experimental Models for Investigating Intestinal Fluid and Electrolyte Transport Isha Dey and Neil A. Bradbury

Section 4. Cell Volume Regulation in the Brain 11. Cell Volume Control in Healthy Brain and Neuropathologies Corinne S. Wilson and Alexander A. Mongin 12. Cytotoxic Swelling of Sick Excitable Cells – Impaired Ion Omeostasis and Membrane Tension Homeostasis in Muscle and Neuron Catherine E. Morris