Neglected Diseases: Extensive Space for Modern Drug Discovery

Medicinal Chemistry Approaches To Overcome Antibiotic Resistance, Volume 51, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies. Topics of note in this release include, but are not limited to, Targeting Human onchocerciasis: recent advances beyond Ivermectin, Leishmaniasi, Tripanosoma Brucei and Tripanosoma Cruzei, Ebola, and Crystallographic approaches in NTDs drug discovery.

Provides the authority and expertise of leading contributors from an international board of authorsPresents the latest release in the Annual Reports in Medicinal Chemistry seriesUpdated release includes the latest information on Medicinal Chemistry Approaches To Overcome Antibiotic Resistance

1. Targeting Human Onchocerciasis: Recent Advances Beyond Ivermectin Stefano Sainas, Franco Dosio, D. Boschi and M.L. Lolli 2. Scaffolds and Biological Targets Avenue to Fight Against Drug Resistance in Leishmaniasis Chiara Borsari, Antonio Quotadamo, Stefania Ferrari, A. Venturelli, Anabela Cordeiro, Nuno Santarem and Maria Paola Costi 3. Drugs and Drug Resistance in African and American Trypanosomiasis Jaime Franco, Laura Scarone and Marcelo A. Comini 4. Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules Elisa Fanunza, Aldo Frau, Angela Corona and Enzo Tramontano 5. X-Ray Crystallography Contributions to Drug-Discovery Against Parasite Infections Cecilia Pozzi, Giusy Tassone and Stefano Mangani