Single-Cell Omics: Volume 1: Technological Advances and Applications

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health.

This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical fieldSummarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosisWritten by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic

Section I Overview of Single-Cell Omics 1. Single-Cell Omics: An Overview 2. Recent Progress in Single-Cell Sequencing 3. Cellular Heterogeneity and Single-Cell Omics 4. Single-Cell Omics: Cellular Functions 5. Single-Cell Omics: Deciphering Tumor Clonal Architecture

Section II Omics Technologies in Single-Cell 6. An Overview of Single-Cell Isolation Techniques 7. Microfluidic Techniques for Single-Cell Culture 8. Single-Cell Omics in Noninvasive Diagnosis and Testing—Surface-Enhanced Raman Spectroscopy-Based Approach 9. Single-Cell Genomics: Technology and Applications 10. Single-Cell Metagenomics 11. Single-Cell Epigenomics: Technology and Applications 12. Single-Cell Transcriptomics: Technology and Applications 13. Single-Cell Transcriptomics and Proteomics of Skeletal Muscle: Technology and Applications 14. Single-Cell Proteomics: Technology and Applications 15. Single-Cell Metabolomics: Technology and Applications 16. Single-Cell Phenomics in Budding Yeast: Technologies and Applications 17. Robotics in Single-Cell Omics 18. Single-Cell Editing: The CRISPR/Cas9 and Applications

Section III Data Analysis in Single-Cell Omics 19. Data Analysis in Single-Cell RNA-Seq 20. Systems-Level Understanding of Single-Cell Omics