Therapeutic Proteins and Peptides

Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more.

Describes advances in the discovery and application of therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects when compared to chemical compounds used for disease treatmentTargeted to a very wide audience of specialists, researchers and studentsWritten by well-renown authorities in their fieldIncludes a number of high quality illustrations, figures and tables

1. Rational Design of Liquid Formulations of Proteins Mark C. Manning, Jun Liu, Tiansheng Li and Ryan E. Holcomb 2. Therapeutic Monoclonal Antibodies Delivery for the Glioblastoma Treatment Flávia Sousa, Rui P. Moura, Elias Moreira, Cláudia Martins and Bruno Sarmento 3. Dynamical Behavior of Somatostatin-14 and Its Cyclic Analogues as Analyzed in Bulk and on Plasmonic Silver Nanoparticles Belén Hernández, Yves-Marie Coïc, Eduardo López-Tobar, Santiago Sanchez-Cortes, Bruno Baron, Fernando Pflüger, Sergei G. Kruglik, Régis Cohen and Mahmoud Ghomi 4. Transglutaminase and Sialyltransferase Enzymatic Approaches for Polymer Conjugation to Proteins Katia Maso, Antonella Grigoletto and Gianfranco Pasut 5. Chimeric Small Antibody Fragments as Strategy to Deliver Therapeutic Payloads Sandra Aguiar, Joana Dias, Ana M. Manuel, Roberto Russo, Pedro M. P. Gois, Frederico A. da Silva and Joao Goncalves 6. Smart Cell-Penetrating Peptide-Based Techniques for Intracellular Delivery of Therapeutic Macromolecules Yang He, Feng Li and Yongzhuo Huang 7. In Silico Tools and Databases for Designing Peptide-Based Vaccine and Drugs Salman S. Usmani, Rajesh Kumar, Sherry Bhalla, Vinod Kumar and Gajendra P.S. Raghava 8. Protein and Peptides for Elderly Health Nan Shang, Chalamaiah Meram, Nandika Bandara and Jianping Wu 9. Peptide Derivates of Erythropoietin in the Treatment of Neuroinflammation and Neurodegeneration Ilkcan Ercan, Kemal U. Tufekci, Ezgi Karaca, Sermin Genc and Kursad Genc 10. The Structure/Function Relationship in Antimicrobial Peptides: What Can we Obtain From Structural Data? Marlon H. Cardoso, Karen G. N. Oshiro, Samilla B. Rezende, Elizabete S. Cândido and Octávio L. Franco 11. Linear Analogues of Lipopeptide Battacin With Potent In Vitro Activity Against S. aureus Hugh D. Glossop, Esperanza Pearl, Gayan H. De Zoysa and Vijayalekshmi Sarojini