The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care

The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory proposing a collaborative approach to resolving global health issues and improve productivity of drug development. The Core Model proposes that scientific collaboration in society does not occur in an "unstructured" manner, but actually takes place within a highly structured order through which knowledge is transferred, integrated, and finally translated into commercial products for the benefit of society. The way in which this is accomplished is via such avenues as an exchange of information, knowledge, experimental results, and personal connections among collaborating parties. This trading of assets among collaborators is the driving force of innovation and, if done correctly, could save time, labor, and economic resources when developing a new drug. The understanding of this model and its application, by the private and public sectors, could help us solve the global pharmaceutical industry´s productivity problems and address important global health care and economic issues, such as having affordable access to high-quality innovative drugs. This book is useful to researchers, advanced students, regulators and management in pharmaceutical industries, as well as healthcare professionals, those working in health economics, and those interested in scientific innovation processes.

Explores current state of the pharmaceutical industry and the global health care sectorIncludes insights from world-leading figures in the pharmaceutical industry, health care sector, federal funding agencies, regulatory bodies, investment sector, entrepreneurship, intellectual property law, philanthropic organizations, and advocacy groupsDevelops in-depth, original concepts, which have important implications in the understanding of and search for potential solutions to the world´s health care crisis

Part I 1. Introduction: the remarkable success story of the development of bortezomib 2. Lessons from the development of bortezomib: the Core Model

Part II 3. The “Core”: when innovation meets leadership 4. “The Bridge”: collaboration is the best catalyst to success 5. “The Periphery”: the efficient use of underused societal resources

Part III 6. Biopharmaceutical intellectual property, financial interests, and the Core Model 7. Global health care crisis, the pharmaceutical industry, and the Core Model 8. The Core Model, innovation, economic growth, development, and policy-making

Part IV 9. Conclusion: the Core Model: a novel economic theory 10. Epilogue: the Core Model and other industries