The Science of Hormesis in Health and Longevity

The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health, in order to inspire and stimulate further research and development in this area. Coverage includes the underlying mechanisms of hormesis including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, among others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, as well as lifestyle interventions to promote health and homoeostasis. Appropriate for researchers of aging and physiology, gerontolgists, clinicians and medical students,

Provides a comprehensive scholarly review of the current state of hormesis in physiology, health, disease and agingIncludes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing novel therapeutic strategies, as well as lifestyle interventions, in order to promote health and homoeostasisOffers a clear understanding of hormesis’ underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and others

Section 1: HISTORY, TERMINOLOGY AND CHALLENGES 1. The dose-response revolution: how hormesis became significant Edward J. Calabrese 2. Mild stress-induced hormesis: hopes and challenges Eric Le Bourg 3. Primary stress response pathways for preconditioning and physiological hormesis Suresh Rattan and Sumangala Bhattacharya

Section 2: CLINICAL AND LIFESTYLE HORMESIS 4. Remote ischemic preconditioning as a form of hormesis Robert A. Kloner 5. Exercise hormesis for health and longevity Zsolt Radak 6. Nutritional hormesis in a modern environment Helen R. Griffiths 7. Phyto-Hormetins in a Clinical Setting Iris R. Bell 8. Intermittent fasting-dietary restriction as a biological hormetin for health benefits Gurcharan Kaur Sr. 9. Hormetic Responses to Ethanol Ingestion: Focus on Moderation and Cardiovascular Protection Ronald J. Korthuis 10. Thermal waters and the hormetic effects of hydrogen sulfide on inflammatory arthritis and wound healing Giovanni Scapagnini

Section 3: HOREMTIC STRESSORS 11. Hormesis through low dose radiation Alexander Vaiserman 12. Metabolic stress – signaling and metabolic adaptation Thorsten Heinzel 13. DNA damage-induced hormetic responses Christian Kosan and Zhao-Qi Wang 14. Pathogen-induced hormetic responses Reinhard Wetzker and Michael Bauer 15. Neuronal stress and its hormetic aspects Britta Qualmann 16. Energetic Stress and Proteodynamics in Aging and Longevity Karyn L. Hamilton 17. Repeated electromagnetic field stimulation in aging and health Felipe Pablo Perez

Section 4: HORMETIC INTERVENTIONS AND NOVEL PERSPECTIVES 18. Hormesis for healthy ageing Suresh Rattan 19. Enhancing sports performance through hormesis Dick Thijsse 20. Circadian regulation of hormesis for health and longevity Anita Jagota 21. A Roadmap for Cross Operationalisation of Resilience Shima Beigi 22. Mindfulness, health and longevity Jesper Dahlgaard, Mimi Yung Mehlsen, Malene Munk Jørgensen, Rikke Katrine Jentoft Olsen, Niels Gregersen, Anne Maj van der Velden and Antonia Sumbundu 23. Buteyko breathing and ketogenic diet as potential hormetins in non-pharmacological metabolic approaches to health and longevity Misha Sakharoff 24. Treating neurodegenerative diseases with low doses of ionizing radiation Jerry Milton Cuttler 25. Interactions with technology as a cognitive, ‘healthy ageing’ hormetic stimulus Marios Kyriazis