Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease

Sirtuins play an intricate role in the pathology, progression, and treatment of several disease entities ranging from neurodegenerative disorders, cardiovascular disease, diabetes and metabolic disease, immune system dysfunction, to reproductive dysfunction, and aging-related disorders. Sirtuin Biology in Medicine fills a significant void that provides a unique resource for elucidating the most recent research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entities.

Scientists, physicians, students and pharmaceutical industry researchers from diverse backgrounds will use Sirtuin Biology in Medicine as the "go-to resource" for both the biology and medical applications that focus upon sirtuins.

Details the basic and clinical role of sirtuins and the broad applicability for siruin biology to be targeted for multiple medical disease entities, leading to the development of novel therapeutic treatmentsElucidates the research and advances on the biology of sirtuins, the application of these pathways upon cellular biology, and the translation of sirtuin pathways for the treatment of multiple disease entitiesSummarize the multi-discipline views and publications for this diverse topic, covering cell development, cardiovascular and pulmonary systems, neurodegenerative disorders, cancer, and metabolism