The Exposome: A New Paradigm for the Environment and Health

The Exposome: A New Paradigm for the Environment and Health is a thoroughly expanded and updated edition of The Exposome: a Primer, which was the first book dedicated to the topic of the exposome. The book outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines.

Genetic factors account for less than half of all complex diseases, meaning the environment has a greater role. However, unlike genetics, there has been no standard or systematic way to measure the influence of environmental exposures on human health. The exposome is an emerging concept that hopes to address this, measuring the effects of life-long environmental exposures on health and how these exposures can influence disease.

This systematic overview addresses topics including "-omics"-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation, and systems biology), and more. Both students and scientists in disciplines including toxicology, environmental health, epidemiology, and public health will benefit from this rigorous yet readable overview. The second edition includes a more in-depth examination of the exposome including full references, further reading, and thought questions.

Addresses an emerging field that connects with other exciting disciplinesAccessible content that can be used as a textbook or for personal edificationWritten by a single author who is a leader in the fieldGreatly expanded from the 1st edition. All chapters have been updated and a number of new chapters have been added reflecting the increasing breadth of knowledge in the field

1. The Exposome: Purpose, Definitions, and Scope 2. Genes, genomes, genomics-advances and limitations 3. Nurturing science 4. The Environment: The Good, the Bad and the Ugly 5. Measuring exposures and their impacts: practical and analytical 6. Innovation and the exposome 7. Pathways and networks 8. Data science and the exposome 9. The Exposome in the Community 10. The Exposome in the Future