Organofluorine Chemistry: Synthesis and Applications

Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of fluorinated nanoscopic materials for drug delivery and catalysis. This book is of use to practitioners working in interdisciplinary areas such as chemical-, biochemical-, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students in working in organofluorine chemistry.

Provides modern synthetic methods and reactions of organofluorine compoundsIncorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals and fine chemicalsFeatures emerging "hot" topics, such as C-H, C-F activation and organometallic catalysisIllustrates recent advances in fluorous reagents and solvents and their applications in green chemistry and catalysis

1. Nucleophilic Fluorination and Fluoroalkylation 2. Electrophilic Fluorination and Fluoroalkylation 3. Free-radical Fluoroalkylation 4. Organotransition Metal Catalysis in Fluorinations and Fluoroalkylations 5. Pharmaceutical Applications of Organofluorine compounds 6. Synthesis and Applications of ¹⁸F-Labeled Compounds 7. Materials Applications of Organofluorine compounds