Basic and Applied Bone Biology

Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology.

Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).

Presents an in-depth overview of skeletal biology, from molecular to organ levelOffers refresher level content for clinicians or researchers outside their areas of expertiseIncludes updated and complete referencesIncorporates expanded study questions at the end of each chapter for further explorationCovers topics relevant to a modern course in skeletal biology

1. Bone Morphology and Organization 2. Bone Cells 3. Local Regulation of Bone Cell Function 4. Bone Modeling and Remodeling 5. Skeletal Imaging 6. Skeletal Hard Tissue Biomechanics 7. Techniques in Histomorphometry 8. Skeletal Genetics: From Gene Identification to Murine Models of Disease 9. Mechanical Adaptation 10. Fracture Healing 11. Craniofacial Biology, Orthodontics, and Implants 12. Skeletal Growth and Development 13. Calcium and Phosphate: Hormonal Regulation and Metabolism 14. Nutrition 15. Hormonal Effects on Bone Cells 16. Metabolic Bone Diseases 17. Pharmaceutical Treatments of Osteoporosis