Sex Differences in Cardiovascular Physiology and Pathophysiology

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular systemDescribes cell signaling pathways involved in sex-associated cardiovascular function and diseasesPuts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Sex Steroid Receptors 1. Androgens, women and cardiovascular disease 2. Estrogen receptor signaling and cardiovascular function 3. The Protective Role of Estrogen and Brain Estrogen Receptors in the Pathogenesis of Hypertension 4. Sex differences in cerebral ischemia

Sex differences in Hypertension 5. Sex differences in the central control of sodium appetite and blood pressure 6. Sex differences in the role of the ATt2 receptor and blood pressure 7. Regulation of Postmenopausal Hypertension

Preeclampsia and longterm consequences 8. Preeclampsia spectrum disorders including PE, E, HELLP, GH and CHTN 9. Preeclampsia: cardiovascular and renal risk during and post pregnancy 10. The Cerebral circulation during pregnancy and preeclampsia

Role of Sex and Atherosclerosis 11. Sex differences and the role of the renin angiotensin system in atherosclerosis and abdominal aortic aneurysms 12. Sex Differences in Coronary Artery Disease

Role of Sex difference in autoimmunity and inflammation 13. Role of Sex Differences in autoimmunity and inflammation 14. Estrogen autoimmunity and Lupus 15. Gender and sex differences in autoimmune type-I diabetes

Sex Differences in Cardiac Function and Remodeling 16. Sex differences in the developmental programming of cardiovascular structure and function 17. Sex specific mechanisms of myocardial hypertrophy and heart failure

Sex steroids and cardiovascular disease, men versus women 18. Benefits and Risks of Testosterone Therapy in Men with Testosterone Deficiency 19. Sex, age and neurovascular control