Polyphenols: Prevention and Treatment of Human Disease

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers the evidence of the powerful health benefits of polyphenols, ranging from protection against cardiovascular disease, cancer, obesity, diabetes, and osteoporosis. This collection represents an international group of experts in polyphenol research and the coverage is appropriately broad, drawing in endocrinology, public health, cardiology, pharmacology, agriculture, and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted insights into the mechanisms of disease. For decades, conventional therapies have proven unsuccessful or have many side effects in the prevention of disease. This reference fills a void in the research field which nutritionists and alternative therapies may be applicable. Advancing research in the understanding and treatment of disease will be widely accepted.

Provides diseases in one volume and expands coverage to neurologyDescribes polyphenol modulation of blood flow and oxygenation, being a potential mechanism of protection to prevent vascular atherosclerosisDescribes how polyphenols and antioxidants frequently change immune defenses and actionsFocuses on most important areas of research and provides insights into their relationships and translational opportunities

1. The Pharmacology of Avenanthramides: Polyphenols
2. Folate Production by Lactic Acid Bacteria
3. A Triterpenoid Commonly Found in Human Diet: Ursolic Acid
4. The Major Flavonoid of Grapefruit: Naringin
5. Structural Evaluation and Toxicological Study of a Bitter Masking Bioactive Flavanone, ‘Eriodictyol’
6. Postprandial Effects of Wine Consumption Along with a Meal on the Main Pathophysiological Systems
7. Cellular and Molecular Mechanisms of Polyphenol-Induced Beneficial Effects on Cardiac Remodeling
8. Effect of Cranberry Polyphenols and Metabolites on Microbial Activity and Impact on Urinary Tract Health
9. Cranberry Polyphenols: Effects on Cardiovascular Risk Factors
10. An Insight of Polyphenols in Lung Cancer Chemoprevention
11. Mushroom Polyphenols as Chemopreventive Agents
12. Pleiotropic Molecular Effects of Dietary Polyphenols Resveratrol and Apigeninin Leukemia
13. The Polyphenolic Compound Apigenin and Applications to Cervical Cancer
14. An Outside-In and a Reciprocal Inside-Out Hypothesis Combining Resveratrol and Its High Affinity Protein NQO2 to Target iASPP for Reinstating the Activation and Stabilization of Dysfunctional WTp53 as a Melanoma Chemopreventive Approach
15. Counteracting Resistance to BRAF V600E Mutation in Melanoma Using Dietary Polyphenols
16. Role of Natural Compounds in Prevention and Treatment of Chronic Lymphocytic Leukemia
17. Polyphenols and Breast Cancer Prevention—A Summary of the Epidemiologic Evidence
18. Resveratrol Inhibitory Effects Against a Malignant Tumor: A Molecular Insight
19. Biological Activity of Resveratrol on an Ovarian Cancer Cell 231
20. Antiarthritic Effects of Turmeric and Curcumin: A Revisit
21. Effects of Polyphenols on Inflammatory-Allergic Conditions: Experimental and Clinical Evidences
22. Polyphenols and Immune System
23. Antioxidants and Polyphenols in Inflammatory Bowel Disease: Ulcerative Colitis and Crohn Disease
24. Red Propolis: Phenolics, Polyphenolics, and Applications to Microbiological Health and Disease
25. Viral Disease and Use of Polyphenolic Compounds
26. Hepatoprotective Effects of Curcumin in Alcohol-Induced Hepatotoxicity: A Memoir on the Preclinical Studies
27. Turmeric and Its Principal Polyphenol Curcumin as a Nontoxic Gastroprotective Agent: Recent Update
28. Anti-inflammatory, Immunomodulatory, and Prebiotic Properties of Dietary Flavonoids
29. Polyphenols and Polyphenol-Derived Compounds from Plants and Contact Dermatitis 349
30. Plant Polyphenols: The Futuristic Bioactive Therapeutics for Skin Care
31. Antiinflammatory Activity of Polyphenols on Dendritic Cells
32. Effects and Usage of a Citrus Compound, Limonene
33. A Phytoestrogen Puerarin and Its Health Effects
34. Galangin as a Plant Phenolic and Usage in Health and Disease
35. Can Green Tea Polyphenols Improve Phenotypes Associated with Down Syndrome?