The Evolution of Molecular Biology: The Search for the Secrets of Life

The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science.

In addition, the book demonstrates how the roots of discovery and advances-and an individual’s own research-have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery.

Expands on the development of molecular biology from the convergence of two independent disciplines, biochemistry and geneticsDiscusses the value of molecular biology in a variety of applicationsIncludes research ethics and the societal implications of researchEmphasizes the human aspects of research and the consequences of such advances to society

1. Beginnings 2. The Origins of Biochemistry 3. The Chemical Structure of Proteins 4. Proteins in Three Dimensions 5. The Origins of Genetics 6. Nucleic Acids 7. The Great Synthesis 8. How DNA is Replicated 9. The Central Dogma 10. The Genetic Code 11. Gene to Protein: The Whole Path 12. Eukaryotes Pose New Problems 13. Differentiation and Development 14. Recombinant DNA: The Next Revolution 15. Understanding Whole Genomes: Creating New Paradigms 16. Whole Genomes and Evolution 17. Practical Applications of Recombinant DNA Technologies