Epigenetics of Cancer Prevention

Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers.

Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies.

Lists natural agents, including nutraceuticals, and their effects on normal or tumor genomeAddresses various epigenetic systems and mechanisms in the regulation and support of the mammalian genomeDiscusses how various parts of dietary phytochemicals can influence or modify epigenetic mechanisms in several types of cancer

Foreword

I. MOLECULAR EPIGENETIC TARGETS OF NATURAL PRODUCTS

1. Genetic and Epigenetic Targets of Natural Dietary Compounds as Anticancer Agents QIWEN SHI, ANUPAM BISHAYEE, AND DEEPAK BHATIA

2. Epigenetic Dietary Interventions for Prevention of Cancer PRADHAN NIBEDITA, KAR SWAYAMSIDDHA, PARBIN SABNAM, SENGUPTA DIPTA, DEB MOONMOON, DAS LAXMIDHAR, AND PATRA SAMIR KUMAR

3. Natural Anticancer Agents: Modifying the Epigenome to Prevent and Treat Cancer KRISTINA ANDRIJAUSKAITE, JAY MORRIS, AND MICHAEL J. WARGOVICH

4. Histone Deacetylase Inhibitors in Cancer Prevention and Therapy SHAHRZAD MOVAFAGH AND AMANDA MUNSON

5. Epigenetic Effects of Curcumin in Cancer Prevention MUTHU K. SHANMUGAM, FRANK ARFUSO, JUDY C. SNG, ANUPAM BISHAYEE, ALAN PREM KUMAR, AND GAUTAM SETHI

6. The Epigenetic Targets of Berry Anthocyanins in Cancer Prevention DINA MOUSTAFA ABO EL-ELLA AND ANUPAM BISHAYEE

7. Isothiocyanates, Epigenetics, and Cancer Prevention SILVIA NOVÍO, MARÍA JESÚS NÚÑEZ-IGLESIAS, AND MANUEL FREIRE-GARABAL

8. Epigenetic Mechanisms of Resveratrol and Its Analogs in Cancer Prevention and Treatment AVINASH KUMAR AND ANAIT S. LEVENSON

9. Epigenetic Mechanisms of Quercetin and Other Flavonoids in Cancer Therapy and Prevention GIAN LUIGI RUSSO AND PAOLA UNGARO

II. ORGAN SPECIFIC EPIGENETIC TARGETS OF NATURAL PRODUCTS

10. Dietary Phytochemicals, Epigenetics, and Colon Cancer Chemoprevention RITIKRAJ ARYA AND SABITA N. SALDANHA

11. Epigenetic Aspects of Hepatocellular Carcinoma Chemoprevention RENATO HEIDOR, ERNESTO VARGAS-MENDEZ, AND FERNANDO SALVADOR MORENO

12. Epigenetic Control of Pancreatic Carcinogenesis and Its Regulation by Natural Products HASEEB ZUBAIR, SHAFQUAT AZIM, MOHAMMAD ASLAM KHAN, GIRIJESH KUMAR PATEL, AAMIR AHMAD, SACHIN PAI, SEEMA SINGH, AND AJAY P. SINGH

13. Phytochemicals as Epigenetic Modifiers for Cancer Management With Special Reference to Lung Cancer TAMILSELVAM RAJAVEL AND KASI PANDIMA DEVI

14. Epigenetics of Prostate Cancer and Novel Chemopreventive and Therapeutic Approaches DIVYA BHAGIRATH, THAO L. YANG, RAJVIR DAHIYA, SHAHANA MAJID, AND SHARANJOT SAINI

15. Prevention of Breast Cancer by Food Bioactives in Relation to Cancer Subtypes: Epigenetic Mechanisms MICAH G. DONOVAN, ORNELLA I. SELMIN, AND DONATO F. ROMAGNOLO

16. Epigenomics of Ovarian Cancer and Its Chemoprevention OURANIA KOUKOURA, STAVROS SIFAKIS, NIKOLAOS GOUTSIAS, IRONTIANTA GKOREZI-NTAVELA, AND JIANNIS HAJIIOANNOU

III. MISCELLANEOUS

17. Dietary and Lifestyle Factors in Epigenetic Regulation of Cancer ESWAR SHANKAR, KARISHMA GUPTA, AND SANJAY GUPTA

18. Epigenetics, Public Health, Lifestyle, and Chemoprevention MASSIMO ROMANI AND BARBARA BANELLI