Advances in Physical Organic Chemistry

Advances in Physical Organic Chemistry, Volume 51, the latest release in the series, is the definitive resource for authoritative reviews of work in physical organic chemistry. It provides a valuable source of information for not only physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. Its hallmark is a quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

Reviews the application of quantitative and mathematical methods to help readers understand chemical problemsProvides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistryCovers organic, organometallic, bioorganic, enzymes, and materials topicsPresents the only regularly published resource for reviews in physical organic chemistryWritten by authoritative experts who cover a wide range of topics that require a quantitative, molecular-level understanding of phenomena across a diverse range of disciplines

1. The Factors Determining Reactivity in Nucleophilic Substitution Einar Uggerud 2. Negative Ion Photoelectron Spectroscopy and Its Use in Investigating the Transition States for Some Organic Reactions Weston T. Borden 3. Probing Transition State Analogy in Glycoside Hydrolase Catalysis Cinzia Colombo and Andrew J. Bennet 4. Phosphate Ester Hydrolysis: The Path From Mechanistic Investigation to the Realization of Artificial Enzymes Marta Diez-Castellnou, Alvaro Martinez and Fabrizio Mancin 5. Physicochemical Aspects of Aqueous and Non-aqueous Approaches to the Preparation of Nucleosides, Nucleotides and Phosphate Ester Mimics David R.W. Hodgson