Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis, Volume 13, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project.

Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world.

Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the fieldUses firsthand narrative accounts to vividly illustrate the challenges and joys involved in advancing the science of organic synthesis

1. The chemistry of Lobelia alkaloids: an inexhaustible source for molecular diversity 2. Cross-Coupling Free Synthesis of Strained and Congested Biaryl Macrocycles 3. Application of metallacycle-mediated annulatiive cross-coupling chemistry to neurotrophic seco-prezizaane natural products 4. Bio-inspired adventures in the total synthesis of cytochalasans and biosynthetically related natural products 5. Total Synthesis of Ipomoeassin F and Its Analogues for Biomedical Research 6. Total synthesis of guaianoids through a strategy powered by organocatalytic [4+3] cycloaddition reactions 7. The Development of Strategies and Tactics Toward the Pseudopterosin Natural Products: Ileabethoxazole As a Platform for Target-Inspired Discovery 8. Total synthesis of the lindenane-associated terpenoids 9. Total Synthesis of Dehaloperophoramidine: Evolution of a Synthesis