Congenital Adrenal Hyperplasia: A Comprehensive Guide

Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important.

The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment.

Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.

Outlines the basics of congenital adrenal hyperplasia and its interrelation with hormones and bodily functionsPresents the known cognitive and emotional aspects of the diseaseReviews multidisciplinary management as well as post-treatment management of the disease

Section One: Congenital adrenal hyperplasia—introduction 1. Physiology of the Adrenal Glands: How Does It Work? 2. How Males and Females Develop 3. Genetics of Congenital Adrenal Hyperplasia 4. Common Forms of Congenital Adrenal Hyperplasia 5. Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia 6. Growth 7. Puberty 8. Biochemical Tests Used for Diagnosis

Section Two: When things go wrong in congenital adrenal hyperplasia 9. Monitoring Long Term Outcomes 10. Growth 11. When Things Go Wrong With Puberty 12. When Things Go Wrong—Weight, Diabetes and Hypertension 13. When Things Go Wrong—Bone Density and Osteoporosis 14. Fertility 15. Sleep and Mood Alterations 16. Abdominal, Skin and Other Problems

Section Three: Treatment for congenital adrenal hyperplasia 17. History of Steroid Development 18. Glucocorticoid Treatment 19. Glucose and Cortisol 20. Hydrocortisone 21. Dosing and the Circadian Rhythm 22. Cortisol and 17-Hydroxyprogesterone 23. Using Profiles to Assess Cortisol Replacement 24. Monitoring Hydrocortisone Therapy 25. Other Hormones and Their Roles 26. Missing a Dose of Hydrocortisone 27. Intravenous, Intramuscular and Other Forms of Hydrocortisone 28. The Pump Method for Achieving a Normal Circadian Cortisol Replacement 29. Stress Dosing for Sick Days, Surgery, Exams and Exercise 30. Practical Information Emergency Kit and School Information 31. Other Treatments for Congenital Adrenal Hyperplasia—Prednisolone, Dexamethasone and Adrenalectomy 32. Fludrocortisone 9 Alpha-Fludrocortisone 33. Travel and Time Zones 34. Thinking Through Blood Results–A Quiz 35. Discussing the Emotional Aspects of Living With Congenital Adrenal Hyperplasia Appendix 1. Converting System International (SI) Blood Measures Into North American Values or Conventional Units Appendix 2. List of Abbreviations