The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy

The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved.

Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.

Provides an introduction to endocannabinoids in the central nervous system and an overview to their functions in the brainPresents information on neurobiological and cellular studies on the role of the cannabinoid signaling system and its implications in human diseasesIncludes well-written overviews of the basics of endocannabinoid system structure and function Contains well-illustrated material, with diagrams, charts, and tablesExplores compelling case studies and their application to chapters written by experts

1. Basic mechanisms of synthesis and hydrolysis of major endocannabinoids 2. Cannabinoid Receptors and their Signaling Mechanisms 3. The endocannabinoid system and Parkinson’s disease 4. The putative role of the endocannabinoids on Schizophrenia 5. The Endocannabinoid System and Human Brain Functions: Insight from Memory, Motor and Mood Pathologies 6. The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy