Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health

Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety.

Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials.

This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.

Uses a schematic, non-exhaustive approach to summarizes the most important research data in this fieldDiscusses the health implications of experimental data in nanotoxicologyPresents a completely revised edition that focuses on the human health impacts of engineered nanomaterials, including many organ-specific chapters

Section A: Engineered nanomaterials: Hazard, exposure, risk assessment 1. Bio–Nano Interactions 2. Physicochemical Characterization 3. Toxicity Tests: In Vitro and In Vivo 4. Computational Approaches 5. Exposure Assessment 6. Biomonitoring 7. Regulation and Legislation 8. Risk Assessment and Risk Management

Section B: Engineered nanomaterials: Adverse effects on human health 9. Respiratory System, Part One: Basic Mechanisms 10. Respiratory System, Part Two: Allergy and Asthma 11. Cardiovascular System 12. Neurological System 13. Immune System 14. Endocrine System 15. Skin 16. Gastrointestinal System 17. Reproduction and Development 18. Genotoxicity and Cancer