Advances in Pathobiology and Management of Paget’s Disease of Bone

Advances in Pathobiology and Management of Paget’s Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget’s disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget’s disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.

Discusses the current research of the nature of Paget’s disease and its response to the latest treatments which are seminal in the management of this diseaseHelps users quickly assess the very latest details on the diverse scientific and clinical aspects of Paget’s disease, as opposed to searching through multiple journal articles in the literaturePresents work from featured leaders in Paget’s disease around the globeServes as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease

1: Clinical Perspectives of Paget’s disease of Bone Tim Cundy, PhD 2: Virus etiology of Paget’s disease Sakamuri V. Reddy, PhD 3: Genetics of Paget’s disease Stuart H. Ralston,MD 4; Developmental aspects of pagetic osteoclasts G. David Roodman, MD 5: Mutant SQSTM1/p62 signaling in Paget’s disease of bone Rob Layfield, PhD 6: Early-onset Paget’s disease and related disorders: gene mutations and their functional consequences Miep H Helfrich 7: Osteosarcoma in Paget’s disease of bone Marc F. Hansen, PhD 8: Paget’s disease of bone; Prognosis and complications Jacques P. Brown, MD 9: Treatment of Paget’s disease Ian R Reid, MD