Neurotoxicity of Nanomaterials and Nanomedicine

Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation.

This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials.

Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials.

Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicologyIncludes the most common nanoparticles, their applications, and mechanismsProvides one of the first books to focus on nanomedicine and neurotoxicity

1. The application of nanomaterials in medicine
2. The route of nanomaterials entering brain
3. The distribution and elimination of nanomaterials in brain
4. The most common neurotoxicity of nanomaterials and their mechanism
5. The application, neurotoxicity and related mechanism of titanium dioxide nanoparticles
6. The application, neurotoxicity and related mechanism of iron oxide nanoparticles
7. The application, neurotoxicity and related mechanism of silver nanoparticles
8. The application, neurotoxicity and related mechanism of Manganese-containing nanoparticles
9. The application, neurotoxicity and related mechanism of silica nanoparticles
10. The application, neurotoxicity and related mechanism of carbon-based nanoparticles
11. The application, neurotoxicity and related mechanism of cationic polymers
12. The application, neurotoxicity and related mechanism of natural polymer-based nanoparticles
13. The strategies to reduce neurotoxicity of nanomaterials and the corresponding mechanism