Introduction to Cancer Metastasis

Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives.

Includes basic biology and translational approaches to organ-specific cancer sitesProvides readers with information on emerging therapeutic targets for cancer metastasisContains contributions from leading researchers around the globe

Part I. Cancer Metastasis From Primary Organs 1. Cancer Metastasis: An Introduction 2. Breast Cancer Metastasis 3. Prostate Cancer Metastasis 4. Lung Cancer Metastasis 5. Cervical Cancer Metastasis 6. Colorectal Cancer Metastasis 7. Metastatic Pancreatic Cancer: Current State and Future Directions 8. Gastric Cancer Metastasis 9. Hepatocellular Carcinoma: Metastatic Disease 10. Metastatic Bladder Cancer 11. Metastatic Cutaneous Squamous Cell Carcinomas 12. Osteosarcoma Metastasis-Prognostic Factors and Treatment Strategies

Part II. Cancer Metastasis To Distant Organs 13. Lymph Node Metastasis 14. Molecular Involvement of the Bone Marrow Microenvironment in Bone Metastasis 15. An Overview on Hepatic Metastasis 16. Pulmonary Metastasis 17. Brain Metastasis: Basic Biology, Clinical Management, and Insight From Experimental Model Systems

Part III. Emerging Targets for Cancer Metastasis 18. Developmental Pathways: Emerging Therapeutic Targets for Cancer Metastasis 19. Emerging Therapeutic Targets for Cancer Metastasis: From the Perspective of Embryo Implantation 20. Wnt Signaling as a Therapeutic Target in Cancer and Metastasis