Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents.

Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areasFocuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cellsFoscuses on the fundamentals and their potential therapeutic and diagnostic applicationsCovers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

1. Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells 2. Cellular Uptake and Sensing Capability of Transition Metal Peptide Conjugates 3. Luminescent Rhenium(I) and Iridium(III) Complexes for Intracellular Labeling, Sensing, and Photodynamic Therapy Applications 4. Organoruthenium(II)-Arene Complexes: Structural Building Blocks for Anticancer Drug Discovery 5. Medicinal Chemistry of Metal N-Heterocyclic Carbene (NHC) Complexes 6. Metal Complexes as Delivery Systems for CO, NO, and H₂S to Explore the Signaling Network of Small-Molecule Messengers 7. Antimicrobial Metallodrugs 8. Carbon Nanotubes and Related Nanohybrids Incorporating Inorganic Transition Metal Compounds and Radioactive Species as Synthetic Scaffolds for Nanomedicine Design 9. Immobilized Metal Affinity Chromatography (IMAC) for Metalloproteomics and Phosphoproteomics 10. The Analysis of Therapeutic Metal Complexes and Their Biomolecular Interactions