Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters.

Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition.

Provides a single source of information on lung epithelial junctions and transportersDiscusses of the role of the epithelium in lung homeostasis and diseaseIncludes capsule summaries of main conclusions as well as highlights of future directions in the fieldCovers the mechanistic basis for lung disease for a range of audiences

1. Junctional Interplay in Lung Epithelial Barrier Function 2. Ion Transport and Lung Fluid Balance 3. Glucose Transport and Homeostasis in Lung Epithelia 4. Pulmonary Surfactant Trafficking and Homeostasis 5. Integrin Regulation of the Lung Epithelium 6. Epithelial Regeneration and Lung Stem Cells 7. The Function of Epithelial Cells in Pulmonary Fibrosis 8. The Role of Epithelial Cell Quality Control in Health and Disease of the Distal Lung 9. The Respiratory Epithelium in COPD 10. Acute Respiratory Distress Syndrome 11. Epithelial Barrier Dysfunction in Asthma 12. Cystic Fibrosis: An Overview of the Past, Present, and the Future