How to Scale-Up a Wet Granulation End Point Scientifically

How to Scale-Up a Wet Granulation End Point Scientifically provides a single-source devoted to all relevant information on the scale-up of a wet granulation end point.

Contents include a general description, problem identification, and theoretical background with supporting literature, case studies, potential solutions, and more. By outlining issues related to scale-up and end-point determination, and then using practical examples and advice to address these issues, How to Scale-Up a Wet Granulation End Point Scientifically is a valuable and essential resource for all those pharmaceutical scientists and technologists engaged in the granulation process.

Thoroughly referenced and based on the latest research and literaturePart of the Expertise in Pharmaceutical Process Technology Series edited by internationally respected expert, Michael LevinIllustrates the most common problems related to scale-up of a wet granulation end point and provides valuable insights on how to solve these problems in a practical way

1. Scale-Up Basics
2. Dimensional Analysis, Principle of Similitude, Dimensionless Numbers, Comparison of attainable Froude Numbers
3. Scientific scale-up procedure
4. Case Studies
5. Practical Considerations for End-Point Scale-Up
6. List of Symbols and Dimensions, Literature Reference