Regulatory T Cells in Health and Disease

Regulatory T Cells in Health and Disease focuses on the mechanism by which T cells become regulatory T cells, the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer.

Contains contributions from leading authorities in the field of regulatory T cell biologyInforms and updates on all the latest developments in the field Explores the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer

1. Transcriptional and Epigenetic Regulation of Regulatory T Cell Development
   Yohko Kitagawa, James Badger Wing and Shimon Sakaguchi
2. Microenvironment Matters: Unique Conditions within Gut Draining Lymph Nodes Favor Efficient de Novo Induction of Regulatory T Cells
   Maria Pasztoi, Joern Pezoldt and Jochen Huehn
3. The Roles of the Nf-Κb Pathway in Regulatory T Cell Development and Function
   Thomas S. Fulford, Darcy Ellis and Steve Gerondakis
4. The Molecular Control of Regulatory T Cell Induction
   Annemarie van Nieuwenhuijze and Adrian Liston
5. The Special Relationship in the Development and Function of T Helper 17 and Regulatory T Cells
   Matthias Lochner, Zuobai Wang and Tim Sparwasser
6. Mechanisms of Surveillance of Dendritic Cells by Regulatory T Lymphocytes
   Maxime Dhainaut and Muriel Moser
7. Development and Function of Effector Regulatory T cells
   Peggy P. Teh, Ajithkumar Vasanthakumar and Axel Kallies
8. Treg Cell Differentiation: from Thymus to Peripheral Tissue
   David M. Richards, Michael Delacher, Yael Goldfarb, Danny Kägebein,  Ann-Cathrin Hofer, Jakub Abramson  and Markus Feuerer
9. Regulatory T Cells in Arthritis
   Noriko Komatsu and Hiroshi Takayanagi
10. The Immune Fulcrum: Regulatory T Cells Tip the Balance Between Pro- and  Anti-Inflammatory Outcomes Upon Infection
    Laura E. Richert-Spuhler and Jennifer M. Lund
11. Regulatory T Cells in Autoimmune Diabetes: Mechanisms of Action and Translational Potential
    Vitalijs Ovcinnikovs and Lucy S.K. Walker