Biomarkers of Kidney Disease

Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.

This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.

Explores both the practical and conceptual steps performed in the discovery of biomarkers in kidney disease Presents a comprehensive account of newer biomarker discover strategies, such as metabolomics and proteomics, all illustrated by clear examplesOffers clear translational presentations by the top basic and clinical researchers in each specific renal disease, including AKI, transplantation, cancer, CKD, PKD, diabetic nephropathy, preeclampsia, and glomerular disease

Preface 1. Characteristics of an Ideal Biomarker of Kidney Diseases Michael R. Bennett and Prasad Devarajan 2. Statistical Considerations in Analysis and Interpretation of Biomarker Studies Chirag R. Parikh, Heather Thiessen Philbrook 3. The Role of Metabolomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools Uwe Christians, Jost Klawitter, Jacek Klepacki and Jelena Klawitter 4. The Role of Proteomics in the Study of Kidney Diseases and in the Development of Diagnostic Tools Uwe Christians, Jelena Klawitter, Jacek Klepacki and Jost Klawitter 5. Cystatin C as a multifaceted biomarker in kidney disease and its role in defining "Shrunken Pore Syndrome" Anders Grubb 6. Biomarkers in acute kidney injury Charles L. Edelstein 7. Biomarkers of extra-renal complications of AKI Sarah Faubel 8. Biomarkers in kidney transplantation Alkesh Jani 9. Biomarkers of Renal Cancer Naveen S. Vasudev and Rosamonde E. Banks 10. Proteomics and Advancements in Urinary Biomarkers of Diabetics Kidney Disease Michael L. Merchant and Jon B. Klein 11. Biomarkers of Cardiovascular Risk in Chronic Kidney Disease Zoltan H. Endre and Robert J. Walker 12. Diagnostic and Prognostic Biomarkers in Autosomal Dominant Polycystic Kidney Disease Godela Fick-Brosnahan and Berenice Y. Reed 13. Biomarkers in Glomerular Disease John M. Arthur, Elwaleed Elnagar and Nithin Karakala 14. Biomarkers in Preeclampsia S. Ananth Karumanchi