Nutrition in the Prevention and Treatment of Disease

Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research

Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding.

Two new chapters on metabolomics and translational research, which have come to be used in nutrition research in recent years. The new areas of study are discussed with the perspective that the application of the scientific method is by definition an evolutionary process.A new chapter on Genetics and Diabetes which reviews the latest research on causal genetic variants and biological mechanisms responsible for the disease, and explores potential interactions with environmental factors such as diet and lifestyle. Includes all major "omics" – the exposome, metabolomics, genomics, and the gut microbiome.Expands the microbiota portions to reflect complexity of diet on gut microbial ecology, metabolism and health

Section I: Research Methodology

Part A: Assessment Methods for Research and Practice 1. Dietary Assessment Methodology 2. Assessment of Dietary Supplement Use 3. Physical and Clinical Assessment of Nutritional Status 4. Energy Requirement Methodology 5. Metabolomics

Part B: Research and Applied Methods for Observational and Intervention Studies 6. Translational Research: Concepts and Methods in Dissemination and Implementation Research 7. Overview of Nutritional Epidemiology 8. Analysis, Presentation, and Interpretation of Dietary Data 9. Current Theoretical Bases for Nutrition Intervention and Their Uses 10. Nutrition Intervention: Lessons From Clinical Trials 11. Biomarkers and Their Use in Nutrition Intervention

Section II: Nutrition for Health Maintenance, Prevention, and Disease-Specific Treatment

Part A: Food and Nutrient Intake for Health 12. Nutrition Guidelines to Promote and Maintain Health 13. Nutritional Recommendations for Athletes 14. Nutrition for Children With Special Health Care Needs

Part B: Dietary Bioactive Compounds for Health 15. Bioavailability and Metabolism of Bioactive Compounds From Foods 16. Antioxidants in Health and Disease 17. Choline and Brain Development 18. Dietary Phytochemicals in Neurodegenerative Disease 19. Diet and Supplements in the Prevention and Treatment of Eye Diseases 20. Phytochemicals in the Prevention and Treatment of Obesity and Its Related Cancers

Part C: Overweight and Obesity 21. Genetics of Nonsyndromic Human Obesity, With Suggestions for New Studies From Work in Mouse Models 22. Obesity: Overview of Medical Treatments and Interventions 23. Surgery for Severe Obesity 24. Behavioral Risk Factors for Overweight and Obesity: Diet and Physical Activity 25. Snacking and Energy Balance in Humans

Part D: Cardiovascular Disease 26. Genetic Influences on Blood Lipids and Cardiovascular Disease Risk 27. The Role of Diet in the Prevention and Treatment of Cardiovascular Disease 28. Nutrition, Lifestyle, and Hypertension

Part E: Diabetes Mellitus 29. Genetics and Diabetes 30. Obesity and the Risk for Type 2 Diabetes 31. The Role of Diet in the Prevention and Treatment of Diabetes 32. Nutritional Management for Gestational Diabetes

Part F: Cancer 33. Interaction of Genetic Factors With Nutrition in Cancer 34. Nutrition and Cancers of the Breast, Endometrium, and Ovary 35. Nutrition and Prostate Cancer 36. Nutrition and Colon Cancer

Part G: Gastrointestinal Health and Disease 37. Intestinal Microbiota and Diet in Health 38. Gut Microbial Metabolism in Health and Disease 39. Nutritional Management of Inflammatory Bowel Disease and Short Bowel Syndrome 40. Nutrient Considerations in Lactose Intolerance 41. Nutritional Considerations in the Management of Gluten-Related Disorders 42. Nutrition and Cystic Fibrosis

Part H: Bone Health and Disease 43. Current Understanding of Vitamin D Metabolism, Nutritional Status, and Role in Disease Prevention 44. Osteoporosis: The Early Years 45. Osteoporosis in Adults