Anti-Angiogenesis Strategies in Cancer Therapies

Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches.

Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences.

Covers important preclinical models and clinical trials in the discovery and development of novel anti-angiogenesis agentsReviews FDA-approved anti-angiogenesis agentsIllustrates the value of nanotechnology in improving the utility of anti-angiogenesis agentsOffers insight into the development of novel anti-angiogenesis agents and future direction in this area

1. Role of Angiogenesis and lymphogenesis in Cancer (tumor growth, Invasion, metastasis 2. Role of Angiogenesis and anti-angiogenesis in hematological malignancies (acute / chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms) 3. The interface between Thrombosis-Inflammation and Angiogenesis 4. Micro RNA and Angiogenesis modulation 5. Preclinical discovery and development of different Pharmacological anti-angiogenesis agents 6. Differences among different anti-angiogenesis strategies (Mechanisms of actions) 7. Naturally Occurring Anti-angiogenesis 8. Clinical trials with anti-angiogenesis agents: Approved agents 9. Angiogenesis Biomarkers and Impact on personalized management 10. Efficacy of Anti-VEGF therapy in cancer 11. Nanotechnology in enhancing the utility of anti-angiogenesis agents – Combinations with other anti-cancer agents 12. Multi-targeted anti-angiogenesis therapy in cancer 13. Combination of anti-angiogenesis and chemotherapeutics 14. Nanotechnology in enhancing the utility of anti-angiogenesis agents – Combinations with other anti-cancer agents 15. Nano-targeted anti-angiogenesis agents in cancer detection 16. Future Directions