Translational Research in Coronary Artery Disease: Pathophysiology to Treatment

Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology.

Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function.

By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source.

Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished dataSummarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery diseaseProvides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Chapter 1: Endothelial Biology - the role of endothelial cells and endothelial progenitor cells
Chapter 2: The Role of Vascular Smooth Muscle Phenotype and Cytochrome P450-Derived Eicosanoids in Coronary Artery Disease
Chapter 3: Inflammation and Coronary Artery Disease
Chapter 4: Adiponectin: A mediator of obesity, insulin resistance, diabetes and the metabolic syndrome
Chapter 5: Use of Stem Cells in Ischemic Heart Disease
Chapter 6: Vasculogenesis and Angiogenesis
Chapter 7: Lipids
Chapter 8: Genetics and Coronary Disease
Chapter 9: Nitric Oxide and Heart Failure in the Presence of Coronary Disease
Chapter 10: Revascularization for Silent Myocardial Ischemia
Chapter 11: Noninvasive Diagnostic Modalities for Evaluation of Coronary Artery Disease
Chapter 12: Current Approaches to Treatment of Ventricular Arrhythmias in Patients with Coronary Artery Disease
Chapter 13: Magnetic Resonance Imaging for Clinical Use and Research Investigation in Coronary Artery Disease
Chapter 14: Invasive Diagnostic Assessment of Coronary Artery Disease
Chapter 15: Drug Treatment of Coronary Artery Disease
Chapter 16: Percutaneous Coronary Intervention of Coronary Artery Disease
Chapter 17: Current Topics in Bypass Surgery
Chapter 18: Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Treatment of Ischemic Shock
Chapter 19: Biostatistics Used for Clinical Investigation of Coronary Artery Disease