Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain

Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications.

Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation.

The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions.

Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brainEdited by renowned leaders in the field of pediatric brain stimulationPresents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry

Section I: FUNDAMENTALS OF NIBS IN CHILDREN
1. TMS basics: Single and paired pulse neurophysiology - Ephrem Zewdie and Adam Kirton
2. Assessing normal developmental neurobiology with brain stimulation - Karina Limburg, Nikolai H. Jung and Volker Mall
3. Neuroplasticity Protocols: Inducing and measuring change - Steve W. Wu and Ernest V. Pedapati
4. Therapeutic rTMS in children - Donald L. Gilbert
5. Transcranial direct current stimulation (tDCS): Principles and emerging applications in children - Adam Kirton and Patrick Ciechanski
6. Insights into pediatric brain stimulation protocols from preclinical research - Alexander Rotenberg
7. Pediatric issues in neuromodulation: Safety, tolerability and ethical considerations - Kathleen M. Friel, Andrew M. Gordon, Jason B. Carmel, Adam Kirton and Bernadette Gillick
Section II: NIBS IN PEDIATRIC NEUROLOGICAL CONDITIONS
8. TMS applications in ADHD and developmental disorders - Donald L. Gilbert
9. TMS mapping of motor development after perinatal brain injury - Martin Staudt
10. The right stimulation of the right circuits: Merging understanding of brain stimulation mechanisms and systems neuroscience for effective neuromodulation in children - Jason B. Carmel and Kathleen M. Friel
11. Therapeutic brain stimulation trials in children with cerebral palsy - Bernadette Gillick, Kathleen Friel, Jeremiah Menk and Kyle Rudser
12. Brain Stimulation in Children Born Preterm – Promises and Pitfalls - Julia B. Pitcher
13. Brain stimulation to understand and modulate the autism spectrum - Lindsay M. Oberman, Alvaro Pascual-Leone and Alexander Rotenberg
14. Clinical applications of brain stimulation in pediatric epilepsy - Sudha Kessler
15. Brain stimulation in pediatric depression: Biological mechanisms - Paul Croarkin, Stephanie Ameis and Frank P. MacMaster
16. Brain stimulation in childhood mental health: Therapeutic applications - Frank P. MacMaster, Mariko Sembo, Keon Ma and Paul Croarkin
17. Transcranial Magnetic Stimulation Neurophysiology of Paediatric Traumatic Brain Injury - Karen Maria Barlow and Trevor Adam Seeger
18. Brain Stimulation Applications in Pediatric Headache and Pain Disorders - Thilinie Rajapakse and Adam Kirton
Section III: INVASIVE BRAIN STIMULATION IN CHILDREN
19. Deep brain stimulation in children: Clinical considerations - Jean-Pierre Lin
20. Deep brain stimulation in children: Surgical considerations - Ratan Bhardwaj
21. Invasive neuromodulation in pediatric epilepsy: VNS and emerging technologies - Manish Ranjan and Walter Hader
22. Emerging Applications and Future Directions in Pediatric Neurostimulation - Donald L. Gilbert and Adam Kirton