Protein Kinases in Development and Disease

Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation of current model organisms from plants and C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease.

Reviews kinases, the fundamental regulators of most biological processes that have key roles in the development of all organismsIncludes a broad scope of topics that are addressedAllows researchers and newcomers to this research area to gain a thorough picture of the current knowledge

1. WNK Kinases in Development and Disease 2. SGK1: The Dark Side of PI3K Signaling 3. Homeodomain-Interacting Protein Kinases: Diverse and Complex Roles in Development and Disease 4. ROR-Family Receptor Tyrosine Kinases 5. Regulation of Drosophila Development by the Golgi Kinase Four-Jointed 6. The Hippo Pathway: A Master Regulatory Network Important in Development and Dysregulated in Disease 7. Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor 8. Glycogen Synthase Kinase 3: A Kinase for All Pathways? 9. CK1 in Developmental Signaling: Hedgehog and Wnt 10. Ligand Receptor-Mediated Regulation of Growth in Plants 11. Regulation of Cell Polarity by PAR-1/MARK Kinase 12. Receptor Tyrosine Kinases and Phosphatases in Neuronal Wiring: Insights From Drosophila 13. VEGF Receptor Tyrosine Kinases: Key Regulators of Vascular Function