Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists

Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences.  This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource.  Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more.  Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.

Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug productsUses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposesIllustrates how to write and evaluate drug registration files

Preface

Chapter 1 - Introduction Chapter 2 – Basic Concepts of Pharmacokinetics Chapter 3 - Physicochemical Properties and Pharmacokinetics Chapter 4 - Drug Pharmacokinetics After Alternative Routes of Administration Chapter 5 - Pharmacologic Response and Drug Dosage Adjustments Chapter 6 - The Effect of Food and Exipients on Drug Pharmacokinetics Chapter 7 - Practice Problems

Appendix I: Answers to Problems in Chapter 7 Appexndix II: Symbols and Abbreviations