Molecular Biology of Eye Disease

This volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of eye disease.

Contributions from leading authorities Informs and updates on all the latest developments in the field

1. Overview of the Visual System J. Fielding Hejtmancik and John M. Nickerson

2. Cornea

2.a. Overview of the Cornea: Structure, Function, and Development Allen O. Eghrari, S. Amer Riazuddin and John D. Gottsch

2.b.  Stem Cells in the Cornea Andrew J. Hertsenberg and James L. Funderburgh

2.c.  Corneal Development: Different Cells from a Common Progenitor Peter Y. Lwigale

2.d.  Corneal Epithelial Wound Healing  Chia-Yang Liu and Winston Whey-Yang Kao

2.e.i. Corneal Dystrophies: Overview and summary Daniel Schorderet

2.e.ii. Fuchs Corneal Dystrophy Allen O. Eghrari, S. Amer Riazuddin and John D. Gottsch

2.e.iii. Molecular Pathogensis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy 2  Eung Kweon Kim, Hun Lee and Seung-il Choi

3. Lens

3.a.  Overview of the Lens J. Fielding Hejtmancik and Alan Shiels

3.b.  Lens Development and Crystallin Gene Expression Ales Cvekl, Rebecca McGreal, and Wei Liu

3.c.  Lens Biology and Biochemistry J. Fielding Hejtmancik, S. Amer Riazuddin, Rebecca McGreal, Wei Liu, Ales Cvekl, and Alan Shiels

3.d.  Molecular Genetics of Cataract Alan Shiels and J. Fielding Hejtmancik

4. Refraction

4.a. RPE and Choroid Mechanisms Underlying Ocular Growth and Myopia Yan Zhang and Christine Wildsoet

4.b.  Scleral Mechanisms Underlying Ocular Growth and Myopia Ravi Metlapally and Christine F. Wildsoet

 4.c. Molecular and Biochemical Aspects of the Retina on Refraction Ranjay Chakraborty and Machelle T. Pardue

4.d.  Genetics of Refraction and Myopia Qingjiong Zhang

5. Ocular Immunity

5.a.  Molecular Genetic Advances in Uveitis Shengping Hou, Aize Kijlstra and Peizeng Yang

6. Aqueous Flow and Intraocular Pressure

6.a.  Intraocular Pressure and the Mechanisms Involved in Resistance the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways Ernst R. Tamm, Barbara M. Braunger and Rudolf Fuchshofer

6.b. Glaucoma Genes and Mechanisms Janey L. Wiggs

6.c. Neuroinflammation in Glaucoma and Optic Nerve Damage Caitlin E. Mac Nair and Robert W. Nickells

6.d. What Animal Models Can Tell Us about Glaucoma Felix L. Struebing and Eldon E. Geisert

7. Retina

7.a. Introduction to the Retina Hans E. Grossniklaus, Eldon E. Geisert and John M. Nickerson

7.b.  Development of the Vertebrate Eye and Retina Deborah L. Stenkamp

7.c.  Insights into the Molecular Properties of ABCA4 and its Role in the Visual Cycle and Stargardt Disease Robert S. Molday

7.d. A History of the Classical Visual Cycle Charles B. Wright, T. Michael Redmond and John M Nickerson

7.e.  A2E and Lipofuscin Rosalie K. Crouch, Yiannis Koutalos, Masahiro Kono, Kevin Schey and Zsolt Ablonczy

7.f. Cone Health and Retinoids Masahiro Kono

7.g.  Retinoid Processing in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelium Cultures Mark A. Fields, Hannah E. Bowrey, Jie Gong, Zsolt Ablonczy and Lucian V. Del Priore

7.h.  Potential Role of Exercise in Retinal Health Machelle T. Pardue, Micah A. Chrenek, Robin H. Schmidt, John M. Nickerson and Jeffrey H. Boatright

7.i. The Biology of Retinoblastoma Pia R. Mendoza and Hans E. Grossniklaus

e-chapter: The 11-cis Retinal Origins of Lipofuscin in the Retina Leopold Adler IV, Nicholas P. Boyer, Chunhe Chen, Zsolt Ablonczy, Rosalie K. Crouch, Yiannis Koutalos