Adenosine Receptors in Neurology and Psychiatry

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas.

1. Adenosine Receptor Neurobiology: Overview

Jiang-Fan Chen, Chien-fei Lee and Yijuang Chern

2. Adenosine Receptor PET Imaging in Human Brain

Masahiro Mishina and Kiich Ishiwata

3. An Overview of Adenosine A_2A Receptor Antagonists in Parkinson’s Disease

Peter Jenner

4. Mode of Action of Adenosine A_2A Receptor Antagonists as Symptomatic Treatment for Parkinson’s Disease

Akihisa Mori

5. Adenosine Receptors and Dyskinesia in Pathophysiology

Masahiko Tomiyama

6. Clinical/Pharmacological Aspect of Adenosine A_2A Receptor Antagonist for Dyskinesia

Tomoyuki Kanda and Shin-ichi Uchida

7. Interaction of Adenosine Receptors With Other Receptors from Therapeutic Perspective in Parkinson’s Disease

Nicolas Morin and Thérèse Di Paolo

8. Effects of the Adenosine A_2A Receptor Antagonist on Cognitive Dysfunction in Parkinson’s Disease

Shin-ichi Uchida, Takako Kadowaki-Horita and Tomoyuki Kanda

9. Clinical Non-Motor Aspect of A_2A Antagonist in PD Treatment

Masahiro Nomoto, Masahiro Nagai and Noriko Nishikawa

10. Adenosine Receptors and Huntington’s Disease

Chien-fei Lee and Yijuang Chern

11. Adenosine Receptors and Epilepsy: Established Evidence and Perennial Potential

Susan A. Masino, Masahito Kawamura, Jr. and David N. Ruskin

12. Adenosine Receptor Control of Cognition in Normal and Disease

Jiang-Fan Chen

13. Adenosine Receptors in Cerebral Ischemia

Alessia Melani, Anna Maria Pugliese, and Felicita Pedata

14. Roles of Adenosine and its Receptors in Sleep-Wake Regulation

Zhi-Li Huang, Ze Zheng and Wei-Min Qu

15. Involvement of Adenosine A_2A Receptors in Depression and Anxiety

Koji Yamada, Minoru Kobayashi and Tomoyuki Kanda

16. The Adenosine Neuromodulation System in Schizophrenia Daniel Rial, Diogo R. Lara and Rodrigo A. Cunha