Advances in Protein Chemistry and Structural Biology

This eclectic volume features two major topics: applications of mass spectrometry in bioscience; and computational methods for analysis of protein structure and interactions with other macromolecules.

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.

Describes advances in application of powerful techniques in a wide bioscience areaChapters are written by authorities in their fieldTargeted to a wide audience of researchers, specialists, and studentsThe information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

1. Bioinformatics Tools to Identify and Quantify Proteins using Mass Spectrometry Data

Soyoung Ryu

2. Unraveling Oxidation-Induced Modifications in Proteins by Proteomics

Carolina Panis

3. Role of Proteomics in Biomarker Discovery: Prognosis and Diagnosis of Neuropsychiatric Disorders

Suman Patel

4. On the use of Knowledge-Based Potentials for the Evaluation of Models of Protein–Protein, Protein–DNA and Protein–RNA Interactions

Oriol Fornes, Javier Garcia-Garcia, Jaume Bonet and Baldo Oliva

5. Algorithms, Applications and Challenges of Protein Structure Alignment

Jianzhu Ma and Sheng Wang

6. Application of Evolutionary based in silico Methods to Predict the Impact of Single Amino Acid Substitutions in Vitelliform Macular Dystrophy

C. George Priya Doss, Chiranjib Chakraborty, N. Monford Paul Abishek, D. Thirumal Kumar and Vaishnavi Narayanan

7. Current State of the Art Molecular Dynamics Methods and Applications

Dimitrios Vlachakis, Elena Bencurova, Nikitas Papangelopoulos and Sophia Kossida

8. Intrinsically Disordered Proteins – Relation to General Model Expressing the Active Role of the Water Environment

Barbara Kalinowska, Mateusz Banach, Leszek Konieczny, Damian Marchewka and Irena Roterman

9. Conformational Elasticity can Facilitate TALE-DNA Recognition

Hongxing Lei, Jiya Sun, Enoch P. Baldwin, David J. Segal and Yong Duan

10. Computational Approaches and Resources in Single Amino Acid Substitutions Analysis towards Clinical Research C. George Priya Doss, Chiranjib Chakraborty, Vaishnavi Narayan and D. Thirumal Kumar