The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation

Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology.

Clonal evolution of the metastasis phenotypeCell Cycle regulationApoptosis in tumour growth and metastasisAngiogenesis in cancerCell surface glycoproteins and their receptorsProteinases and their inhibitors in cancer invasionOncogenes and cancer metastasisDevelopmental genesTumour suppressor genesMetastasis suppressor genesDominant metastasis-associated genes

Clonal Evolution of Metastasis
Inefficiency of the Metastatic Process
Tumor Growth and Metastatic Potential
Cell Cycle Regulation and Metastasis
Apoptosis in Tumor Growth and Metastasis
Angiogenesis in Cancer
Cell Surface Glycoproteins and Their Receptors
Proteinases and Their Inhibitors in Cancer Invasion
Oncogenes and Cancer Metastasis
Developmental Genes and Their Putative Tumor Suppressor Function
Tumor Suppressor Genes
Metastasis Suppressor Genes
Dominant Metastasis Associated Genes