Free Radical Chain Reactions in Organic Synthesis

Written for both the experienced practitioner and the newcomer, this book provides essential guidance to the practical aspects of free radical chain reactions. The book presents tried and tested synthetic schemes as well as a selection of recently developed methods describing rationally designed, highly efficient syntheses giving high yield interconversions of functional groups and carbon*b1carbon bond formation under mild, neutral conditions.

Written by two experienced practitioners in the field, this volume explodes the myth that free radicals are highly reactive, non-selective intermediates.

Contains an extensive introduction discussing principles, advantages, and disadvantages of radical chain reactionsDemonstrates functional group interconversions by radical chain reactionsLists carbon*b1carbon bond formationsPresents inter- and intramolecular radical chain reactionsIncludes many examples and experimental details selected by experienced practitioners in this field

Some Basic Concepts of Free Radical Chain Reactions. Books and Review Articles. Substitution Reactions. Olefin Forming *gb-Elimination Reactions. Preparative Free Radical Rearrangement Reactions. Intermolecular Carbon*b1Carbon Bond Forming Free Radical Chain Reactions. Intramolecular Carbon*b1Carbon Bond Forming Free Radical Chain Reactions. Chapter References. Index of Compounds and Methods.