Chemistry and Biology

Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind.

Indispensable reference work written by leading experts in the fieldProvides up-to-date, timely reviews on compounds and classes of great interestCovers synthesis, biosynthesis, biology, as well as isolation and structure elucidationAn essential research tool for anyone working with alkaloids from a chemical or biological perspective

D. McLean and V. Snieckus, H.F. Manske: Fifty Years of Alkaloid Chemistry. Atta-ur-Rahman and I. Chaudhary, Chemistry and Biology of Steroidal Alkaloids. A. Brossi, Biological Activity of Unnatural Alkaloid Enantiomers. J. Daly, The Nature and Origin of Amphibian Alkaloids. D. Groger and H. Floss, Biochemistry of Ergot Alkaloids: Achievements and Challenges. A. Guggisberg and M. Hesse, Natural Polyamine Derivatives: New Aspects of Their Isolation, Structure Elucidation, and Synthesis. T.M. Kutchan, Molecular Genetics of Plant Alkaloid Biosynthesis. I. Ninomiya, T. Kiguchi, and T. Nato, Pseudodistomins: Structure, Synthesis, and Pharmacology. J.E. Saxton, Synthesis of Aspidosperma Alkaloids. C. Szantay, Synthetic Studies of Alkaloid Chemistry. H. Tajkayama and S-I. Sakai, Monoterpenoid Indole Synthesis Utilizing Biomimetic Reactions. R. Verpoorte, van der Heiden, and Memelink, Plant Biotechnology and the Production of Alkaloids: Prospects of Metabolic Engineering. M. Wall and M. Wani, History and Future Prospects of Camptothecin and Taxol. P.G. Waterman, Alkaloid Chemosystematics.