Strategies and Tactics in Organic Synthesis

This is a unique account of the synthesis of organic molecules. All of the contributors are acknowledged experts in organic synthesis.

D.L. Boger, Diels*b1Alder Reactions of Heterocyclic Azadienes: Development of a Strategy for the Total Synthesis of Streptonigrin, Lavendamycin, and Synthetic Quinoline-5,8-Quinones. S.D. Burke, Studies in Sesquiterpene Synthesis: (+-)-Quadrone (+)-Phyllanthocin. T.A. Engler, The Total Synthesis of Retigeranic Acid. B. Fraser-Reid and R. Tsang, Carbocycles from Carbohydrates: The "Annulated Sugar" Approach. P. Helquist, *gd-Valerolactone Annulation: Application to the Total Synthesis of Quadrone. P.A. Jacobi, The Total Synthesis of Saxitoxin. M.E. Jung, Problem Solving in Organic Synthesis: The False Steps, Failed Pathways, and Ultimately Successful Route to the Bottom Half of Ivermectin. A.P. Kozikowski and M.N. Greco, Synthesis of the Indole Alkaloid *ga-Cyclopiazonic Acid (*gaCA) by Two Sulfur-Mediated Reactions: Discovery of a Useful Diorganozinc Reaction. S.F. Martin, A Unified Strategy for the Synthesis of Alkaloids of the Yohimboid, Heteroyohimboid, and Corynantheioid Families. W.R. Roush, Evolution of a Strategy for the Synthesis of Olivomycin A: Development of Methodology for the Diastereo- and Enantioselective Synthesis of Carbohydrates from Acyclic Precursors. A.B. Smith III and B.D. Dorsey, Evolution of a Synthetic Strategy, Part II: Total Synthesis of (-)-Casbene and (-)-Bertyadionol. D.D. Sternbach, A New Strategy for the Synthesis of Polyquinanes. D.R. Williams, Explorations toward Pseudomonic Acid C. Each chapter includes references. Index.