Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy

Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo.

Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection through synthesis, computations, or experimental applications.

Reviews all current advances in radical detectionEmphasizes chemical structures and reaction schemes fundamental to radical detection and identificationDescribes the uses, advantages, and disadvantages of various probe designsExamines new approaches to radical probe development

Chapter 1. Introduction

Chapter 2. Chemistry of Reactive Species

Chapter 3. Reactive Species in Biological Systems

Chapter 4. Fluorescence Technique

Chapter 5. EPR Spin Trapping

Chapter 6. UV–Vis Absorption and Chemiluminescence Techniques

Chapter 7. Electrochemical, Mass Spectroscopic, Immunochemical, and Nuclear Magnetic Resonance Techniques