Imaging of the Human Brain in Health and Disease

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases.

Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease.

This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease.

A focused introduction to imaging healthy and diseased brainsFocuses on the primary neurotransmitter releaseIncludes sigma, acetylcholine, opioid, and dopamine receptorsPresents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Chapter 1: Neuroimaging of Addiction – N. Volkow

Chapter 2: Brain PET Imaging in the Cannabinoid System - Wong et al.

Chapter 3: Brain Imaging of Cannabinoid Receptors - Casteels et al.

Chapter 4: Human Brain Imaging of Opioid Receptors: Application to CNS Biomarker and Drug Development - Udi E. Ghitza

Chapter 5: Brain Imaging of Sigma Receptors - Sakata et al.

Chapter 6: Human Brain Imaging of Acetylcholine Receptors - Toyohara et al.

Chapter 7: Human Brain Imaging of Adenosine Receptors - Mishina et al.

Chapter 8: Human Brain Imaging of Dopamine D1 Receptors - Fujiwara et al.

Chapter 9: Human Brain Imaging of Dopamine Transporters - Varrone et al.

Chapter 10: Imaging of Dopamine and Serotonin Receptors and Transporters - Felicio et al.

Chapter 11: Imaging the Dopamine D3 Receptor In Vivo - Slifstein et al.

Chapter 12: Dopamine Receptors and Dopamine Release - R. Kessler

Chapter 13: Dopamine Receptor Imaging in Schizophrenia: Focus on Genetic Vulnerability - Hirvonen et al.

Chapter 14: Human Brain Imaging In Tardive Dyskinesia - Chatziioannou et al.

Chapter 15: Human Brain Imaging of Autism Spectrum Disorders - Brasic et al.

Chapter 16: Radiotracers Used to Image the Brains of Patients with Alzheimer ’s Disease - George et al.

Chapter 17: Human Brain Imaging of Anger - Ghaznavi et al.

Chapter 18: Imaging Pain in the Human Brain - Loggia et al.

Chapter 19: Imaging of Neurochemical Transmission in the Central Nervous System - Deuitch et al.

Chapter 20:  Characterizing Recovery of the Human Brain following Stroke: Evidence from fMRI Studies - La et al.